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    Results
    It was found that, in both participants, RMR increased considerably after treatment and after continuing the T2 usage for a further 3 weeks (at 300 mcg/day), body weight was reduced significantly (p<0.05) (about 4%), while the serum levels of FT3, FT4 and TSH, were unchanged.
    It is also important to note that there were no cardiac side effects observed in either participant and that no significant change was observed in the same participants when receiving the placebo.
    Our Comments

    This study supports the hypothesis that 3,5-diiodo-L-thyronine (T2) and 3,3 diiodo-L-thyronine increases the RMR and reduces body weight  in humans without undesirable side effects.

    Factors were controlled closely during this study, focusing on a small group of participants, controlling diet, and ensuring that post and pre study biological values were recorded, such as body weight, body mass index, blood pressure etc.

    Using T2 seems an effective way to boost RMR function and aid weight loss; this is clear from the human study.

    PHARMACEUTICAL GRADE †
    ADVANCED THERMOGENIC FORMULATION †
    EXPLOSIVE ENERGY †
    ADVANCED APPETITE CONTROL †
    RAPID RELEASE CAPSULES †

     

    CAFFEINE ANHYDROUS
    What’s the difference between caffeine and caffeine anhydrous?
    The difference has to do with the amount of water associated with the caffeine molecule. The term “caffeine” can refer to any form of caffeine, regardless of its water content. “Caffeine anhydrous” has essentially no water—just 0.5%. For this reason, logic and chemistry suggest that anhydrous caffeine is more potent. The anhydrous form could also be more potent because, according to some evidence, the body may absorb it more readily.

     

    SYNEPHRINE
    If you’re looking to boost your rate of fat loss and ramp up your results, synephrine is here for you!* Synephrine is an adrenergic amine that stimulates beta-3 receptors, allowing for the release of adrenaline and noradrenaline, and at the same time minimally impacts other receptor sites.* This means synephrine supports a fast metabolic rate with minimal affect on heart rate or blood pressure, as opposed to caffeine or other stimulants.*
    Because synephrine works by stimulating the beta-3 receptors in the body, it supports the breakdown of stored body fat so you can burn that fat efficiently during your workout period.* Synephrine is a double-edged sword that supports your energy and fat-burning efficiency during your workout, and also may help fight off those cravings from trying to trim up.* Synephrine is designed to support:
    High energy levels †
    Suppressing appetite †
    Efficient calorie burning †

     

    FORSKOLIN
    Forskolin is an active compound that is extracted from the Coleus Forskohlii plant. The plant is related to mint, historically grows in India, and has been used in traditional Indian medicine for hundreds of years. Research is still being done to identify how this natural plant extract, Forskolin, works to support the fitness lifestyle, but one thing is certain – Forskolin may help support your goal of body transformation.* If you are looking to burn body fat, build lean muscle mass and improve your body composition, Forskolin may help!* Forskolin supplements have many benefits for the fitness enthusiast. Forskolin may help:
    Promote healthy testosterone level †
    Support lean muscle mass and strength †
    Promote healthy body composition †
    Support fat loss †
    Promote healthy metabolism †
    Encourage optimal thyroid function †

    If you are dedicated to transforming your body, and you’re already committed to a balanced diet and active exercise program, supplementing with Forskolin may help support your goals!

     

    GREEN TEA
    Green tea is a supplement that offers many known health benefits and it’s said more and more are being discovered every day – Making it a wonder supplement! Green tea originated in China and has been used for thousands of years, because of its huge antioxidant complex that can be utilized by the body in many different ways.
    Green tea is a remarkable substance that can optimize your calorie burn rate (metabolism) for fat loss.* By increasing your overall metabolic rate, green tea can be used in combination with exercise to promote optimal calorie burn so you can move closer to your fat loss goals.*
    Green tea may also help to support a healthy immune system, so if want to shed body fat and support overall health, you should consider a green tea supplement.*
    Green tea has naturally occurring caffeine within it, so it can be used to help promote energy levels.* However, the great thing about green tea is that in addition to the caffeine it also provides antioxidant protection, making it a great choice for fighting off body fat during exercise.* Green tea’s biggest benefits include:
    Antioxidant protection for optimal overall health †
    Healthy energy levels †
    Enhanced focus and concentration †
    Optimal metabolic rate †

     

    N-ACETYL-TYROSINE
    What does it do and how does it benefit people?
    N-ACETYLE-TYROSINE may help athletes avoid over training by supporting energy levels.* As an essential part of how dopamine is produced, L-tyrosine may:
    Heighten mental alertness †
    Promote feelings of well being †
    Offset physical and mental fatigue †
    Support metabolism †
    Protect skin integrity †

     

    3,3 DIIDO I THYRONINE, 3,5 DIIDO I THYRONINE
    One non-stimulant ingredient that has received an abundance of positive anecdotal feedback is the ingredient 3,5-diiodo-L-thyronine (T2) and 3,3 diido-L-thyronine (T2), found in NAN THERMO EVOLUTION which works similarly to how thyroid hormone does . A recent study was conducted to find out what effects 3,5-diiodo-L-thyronine (T2) and 3,3 diido-L-thyronine (T2) had on the RMR (Resting Metabolic Rate: the rate at which your body burns calories while you rest) and weight gain in rats on a high fat  content diet.
    The study indicated that these compounds did prevent weight gain in the rats on a high fat diet and stimulated the RMR of the rats.
    A second study was conducted to explore these findings further in 2011. Antonelli et al at the University of Pisa, Italy, engineered an experiment that investigated long term administration of T2 on humans.
    Two subjects, with normal thyroid function, volunteered to receive the T2 compounds. Their body weight, body mass index, blood pressure, heart rate, electrocardiogram, thyroid and liver ultrasonography, glycemia, total cholesterol, triglycerides, free T3 (FT3), free T4 (FT4), T2, thyroid stimulating hormone (TSH) and RMR were assessed and recorded at baseline and at the end of treatment.